Bespoke / Injectables / Letybo

A modern
frown-line
answer.

Fifteen minutes, no downtime. Two or three days later, the 11s between your brows start to ease — and you still look like you, with every smile and lift intact.

Letybo® (letibotulinumtoxinA) FDA-approved 2024
Letybo
— at a glance
Treatment
~15 minutes
First results
2 — 3 days
Peak
7 — 14 days
Lasts
3 — 4 months
Plan
3 — 4 visits / year
Downtime
None
Investment
●●○○
The treatment

What it is.

You come in, we map the two small muscles that pull your brows into a knot, and a few micro-injections later you're out the door — about fifteen minutes, no bruising plan, no recovery day.

By day two or three the crease starts to soften. By day seven to fourteen it's gone — but your forehead still moves, your smile still reaches your eyes. The effect rides for three to four months, then gently fades.

Letybo is the newest neurotoxin on the U.S. market — FDA-approved in 2024 and already one of the most-used in the world. A clean, modern choice if you're starting out, or if you want to try something fresh alongside what you already know.

Treated areas  ·  Glabella (11s)  ·  Forehead  ·  Crow's feet  ·  Brow lift  ·  Lip flip  ·  Jawline  ·  Neck bands

#1
Why now matters

Before it ever reached the U.S., Letybo was the most-used botulinum toxin in South Korea — the country that performs more aesthetic injectables per capita than anywhere on earth. Now it's here, and worth knowing about as you plan your next round.

Clinician administering a cosmetic injection to a patient's face
Who it's for

Where it fits.

Why patients choose it

What you'll notice.

Three things patients tell us over and over after their first Letybo visit — and why they come back.

01

The 11s, gone

That vertical crease that makes you look tired or worried — softened where it forms, the small muscles that pull your brows together quietly let go.

02

Still looks like you

Conservatively dosed and mapped to your face — not a template. You'll laugh, frown, raise an eyebrow. The line goes; the expression stays.

03

Something new to try

Approved in 2024 and already one of the most-used neurotoxins worldwide — a current option if you've plateaued on what you've been using.

The honest comparison

Letybo or Dysport?

Same active molecule, same family. Dysport has a 15-year on-shelf record and the widest range of off-label refinement we reach for. Letybo is the newest U.S.-cleared option and the most narrowly indicated — we use it almost exclusively on label, where its glabellar evidence is excellent.

The well-studied workhorse
Dysport®
The newest U.S. option
Letybo®
FDA-approved
2009 — cosmetic glabella, cervical dystonia, pediatric spasticity, hyperhidrosis
2024 — cosmetic glabellar lines only
On-label cosmetic use
Glabellar (11s) — plus many off-label cosmetic uses refined over fifteen years (forehead, lip flip, masseter, neck bands, hyperhidrosis)
Glabellar (11s) only. Off-label use is possible but the on-label evidence is narrowest
Onset
2 — 3 days, peak ~2 weeks
2 — 3 days, peak ~2 weeks
Typical longevity
3 — 4 months
3 — 4 months
Who it's for
Anything beyond classic 11s — lip flip, masseter, neck bands, hyperhidrosis, broad-forehead diffusion
Classic glabellar (11s) softening, patients curious about the newest formulation
Before you book

What patients actually ask.

The questions that come up most often when someone is trying Letybo for the first time — or thinking about switching from what they've been using.

How soon will I see it working?

Most patients notice the first softening around day two or three. The full effect lands between day seven and fourteen — that's when we ask you to come back if anything still needs a touch.

Will I look frozen or surprised?

No — and that's the entire point of how we dose. We map the two small muscles that pull your brows into a knot, treat only what's pulling, and leave the rest of your face to do what it does. You should still raise an eyebrow, frown, and have your smile reach your eyes.

How is Letybo different from Botox or Dysport?

It's the same drug family — botulinum toxin type A — with a slightly different formulation. Letybo is the newest on the U.S. market, FDA-approved in 2024 after years of use abroad. Onset and duration sit right in the same range as Botox. The choice usually comes down to what your face has responded to historically and what feels right for this season.

Can I switch to Letybo if I've been using something else?

Yes — and many of our patients do, just to see. We'll take a careful history of what dose you've been on, how long it's been lasting, and whether you've noticed any drift. Switching is straightforward; the only reason to wait is if your last round hasn't worn off yet.

When does it wear off — and what happens then?

Around three to four months, the line returns gradually — no sudden snap-back. Most patients schedule the next visit when they first start to see movement creeping back, which lands at three or four visits a year.

Is it safe to use long-term?

Botulinum toxin type A has one of the longest aesthetic safety records of any injectable — decades of use, hundreds of millions of treatments worldwide. Letybo specifically was in wide clinical use abroad for years before the FDA cleared it here. Side effects are usually localized and short-lived; we'll walk through your specific picture at the consult.

Begin

A modern start.

Letybo treatments begin with an unhurried conversation — your anatomy, your expression, and how lightly the touch should land.

Membership Members save on every visit Bank monthly credit toward neurotoxin, dermal filler and skin — so maintenance costs less and your results never lapse. Explore memberships Financing Start now, pay over time Flexible monthly plans through Cherry let you begin treatment today and spread the cost comfortably. See financing options Take it home Extend it with medical-grade skincare Physician-selected serums and SPF protect and prolong your in-office results between appointments. Shop products
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